回帖：可以配置AD站点为Exchange的Hub站点来自定义路由，当然你需要先定义AD站点。
相关资料：
Configure a Hub Site
https://technet.microsoft.com/en-us/library/bb232079%28v=exchg.141%29.aspx?f=255&MSPPError=-2147217396
Understanding Message Routing
https://technet.microsoft.com/en-us/library/aa998825(v=exchg.141).aspx